Woolly mammoth teeth reveal the world’s oldest microbial DNA

Scientists have uncovered microbial DNA preserved in mammoth remains dating back more than one million years, revealing the oldest host-associated microbial DNA ever recovered. By sequencing nearly 500 specimens, the team identified ancient bacterial lineages—including some linked to modern elephant diseases—that coexisted with mammoths for hundreds of thousands of years. These discoveries shed light on the deep evolutionary history of microbes, their role in megafaunal health, and how they may have influenced adaptation and extinction.